Haiteng Deng

Research Interests: Developing and applying technologies and methods in proteomics, metabolomics, and chemical biology. Investigating the functions and mechanisms of redox biology in aging and diseases. Developing biomarkers related to aging and associated diseases. Discovering natural small molecules, nanobodies, and vaccines that improve healthspan. Studying pathogen-host cell interactions. Identifying markers for early tumor diagnosis and investigating the modification and mechanisms of protein therapeutics.

Wang T, Yang C, Li Z, Li T, Zhang R, Zhao Y, Cheng T, Zong Z, Ma Y, Zhang D, Deng H., Flavonoid 4,4′-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy, Redox Biol. 2024 Feb;69:103017.

Yingying Ma; Meiqi Yi; Weixuan Wang; Xiaohui Liu; Qingtao Wang; Chongdong Liu; Yuling Chen; Haiteng Deng; Oxidative degradation of dihydrofolate reductase increases CD38-mediated ferroptosis susceptibility, Cell Death & Disease, 2022, 13(11): 944-953.

Wang W, Yang C, Wang T, Deng H., Complex roles of nicotinamide N-methyltransferase in cancer progression, Cell Death Dis. 2022 Mar 25;13(3):267.

Songbiao Zhu; Wenxi Ding; Yuling Chen; Weixuan Wang; Renhua Xu; Chongdong Liu; Xiaohui Liu; Haiteng Deng, High VHL Expression Reverses Warburg Phenotype and Enhances Immunogenicity in Kidney Tumour Cells, Genomics, Proteomics & Bioinformatics, 2021 Feb 26:S1672-0229.

Yang C, Zhu S, Chen Y, Liu Z, Zhang W, Zhao C, Luo C, Deng H., Flavonoid 4,4′-dimethoxychalcone suppresses cell proliferation via dehydrogenase inhibition and oxidative stress aggravation. Free Radic Biol Med. 2021 Nov 1; 175:206-215.