杨靖 Jing Yang

杨靖研究员专注于质谱化学蛋白质组学,主攻蛋白氧化修饰,整合先进计算手段与传统化学知识,致力于开发新的化学蛋白质组探针与方法,推动氧化还原生物学研究,扩展蛋白质组上的”可药靶”空间。其标志性成果包括：（1）基于计算技术的新型化学蛋白质组探针评估方案；（2）基于计算辅助评测的化学蛋白质组新探针研发；（3）基于化学蛋白质组分析的”可药靶”发现。杨靖研究员同时是科技部”生物大分子与微生物组”重点研发计划专家组成员（A组）,负责蛋白质组学方向的指南制定；作为人体蛋白质组导航计划（首个在广东省实施的国际大科学计划）团队核心成员,参与国际总部（广州）建设等方面的工作。

Researcher Yang Jing specializes in mass spectrometry-based chemical proteomics, focusing on protein oxidative modifications. By integrating advanced computational methods with traditional chemical knowledge, she is dedicated to developing new chemical proteomics probes and methods, advancing redox biology research, and expanding the “druggable” space on the proteome. Her landmark achievements include: (1) Novel chemical proteomics probe evaluation schemes based on computational technology; (2) Development of new chemical proteomics probes based on computation-assisted evaluation; (3) Discovery of “druggable” targets based on chemical proteomics analysis. Researcher Yang Jing is also a member of the Ministry of Science and Technology’s “Biological Macromolecules and Microbiome” Key Research and Development Program Expert Group (Group A), responsible for formulating guidelines in proteomics direction. As a core team member of the Human Proteome Navigation Program (the first international mega-science program implemented in Guangdong Province), she participates in the construction of the international headquarters (Guangzhou).

荣誉奖励
1. 国家自然科学基金优秀青年基金
2. 北京市青年拔尖人才
3. 北京市科技新星

Honors and Awards
1. National Natural Science Foundation Excellent Young Scientists Fund
2. Beijing Outstanding Young Talent
3. Beijing Rising Star of Science and Technology

1. He J#, Fei Z#, Fu L, Tian C, He F, Chi H*, Yang J*.2022.A modification-centric assessment tool for the performance of chemoproteomic probes. Nature Chemical Biology.18(8):904-912.
2. Meng J#, Fu L#, Liu K, Tian C, Wu Z, Jung Y, Ferreira R, Carroll KS, Blackwell TK*, Yang J*. 2021. Global profiling of distinct cysteine redox forms reveals wide-ranging redox regulation in C. elegans. Nature Communications. 12(1):1415.