Lei Zheng

Research Areas:
1. Clinical applications, physiological and pathological mechanisms, and detection technologies of novel “liquid biopsy” biomarkers such as circulating rare cells, extracellular vesicles, and cell-free nucleic acids;
2. Biomedical applications of advanced functional materials and cutting-edge technologies including biosensors, novel fluorescent molecules, and DNA nanotechnology;
3. Applications of artificial intelligence and big data in laboratory medicine.

Selected Publications：
1. Feng J, Xiu Q, Huang Y, Troyer Z, Li B, Zheng L. Plant-Derived Vesicle-Like Nanoparticles as Promising Biotherapeutic Tools: Present and Future. Adv Mater. 2023 Jun;35(24):e2207826. doi: 10.1002/adma.202207826. Epub 2023 Apr 9. PMID: 36592157.（IF：27.4）
2. Pan W, Wu B, Nie C, Luo T, Song Z, Lv J, Tan Y, Liu C, Zhong M, Liao T, Wang Z, Yi G, Zhang L, Liu X, Li B, Chen J, Zheng L. NIR-II Responsive Nanohybrids Incorporating Thermosensitive Hydrogel as Sprayable Dressing for Multidrug-Resistant-Bacteria Infected Wound Management. ACS Nano. 2023 Jun 27;17(12):11253-11267. doi: 10.1021/acsnano.2c10742. Epub 2023 Jun 14. PMID: 37314783.（IF：15.8）
3. Ou Z, Situ B, Huang X, Xue Y, He X, Li Q, Ou D, He B, Chen J, Huang Y, Deng L, Zhang M, Wang Q, Zheng L. Single-particle analysis of circulating bacterial extracellular vesicles reveals their biogenesis, changes in blood and links to intestinal barrier. J Extracell Vesicles. 2023 Dec;12(12):e12395. doi: 10.1002/jev2.12395. PMID: 38050834; PMCID: PMC10696524.（IF：15.5）
4. Wu B, Pan W, Luo S, Luo X, Zhao Y, Xiu Q, Zhong M, Wang Z, Liao T, Li N, Liu C, Nie C, Yi G, Lin S, Zou M, Li B, Zheng L. Turmeric-Derived Nanoparticles Functionalized Aerogel Regulates Multicellular Networks to Promote Diabetic Wound Healing. Adv Sci (Weinh). 2024 May;11(18):e2307630. doi: 10.1002/advs.202307630. Epub 2024 Mar 5. PMID: 38441389; PMCID: PMC11095230.（IF：14.3）