Ying Zhang
委员 Member
Zhang Ying, Associate Researcher, Institutes of Biomedical Sciences, Fudan University. She received her Ph.D. in Science from the Department of Chemistry, Fudan University in 2009, and then stayed at the university, successively serving as assistant researcher and associate researcher; in 2017, she went to the Department of Biochemistry, Purdue University, USA for visiting and study. She has long been engaged in research on highly sensitive and highly selective mass spectrometry analysis methods for glycoproteome and glycome, and has developed various chemical reaction enrichment and small molecule derivatization methods, significantly improving glycoprotein enrichment efficiency and glycan mass spectrometry detection sensitivity, and shortening experimental time. In the past five years, she has published more than 20 SCI papers as first author or corresponding author, received the “Shanghai Youth Science and Technology Rising Star” (2015), and has been invited to give reports at international academic conferences (such as the International Symposium on Glycoconjugates, American Society for Mass Spectrometry Annual Meeting, etc.) many times.
Research Direction:
Research on highly sensitive and highly selective mass spectrometry analysis methodologies for glycoproteome and glycome.
1. Yang L, Peng Y, Jiao J, Tao T, Yao J, Zhang Y*, Lu H*. Metal element chelated tag labeling (MeCTL) for quantitation of N-Glycans in MALDI-MS. Anal Chem. 2017; 89:7470–7476.
2. Zhang Y, Yu M, Zhang C, Wang Y, Di Y, Wang C*, Lu H*. Highly specific enrichment of N-glycoproteome through nonreductive amination reaction using Fe3O4@SiO2-Aniline nanoparticles. Chem Commun. 2015; 51:5982.
3. Zhang Y, Zhang C, Jiang H, Yang P, Lu H*. Fishing the PTM proteome with chemical approaches using functional solid phases. Chem Soc Rev. 2015; 44:8260–8287.
4. Zhang Y, Yu M, Zhang C, Wang C*, Lu H*. Highly selective and ultra rapid solid-phase extraction of N-glycoproteome by oxime click using aminooxy-functionalized magnetic nanoparticles. Anal Chem. 2014; 86:7920–7924.
5. Zhang Y, Kuang M, Zhang L, Lu H*, Yang P. An accessible protocol for solid-phase extraction of N-linked glycopeptides through reductive amination by amine-functionalized magnetic nanoparticles. Anal Chem. 2013; 85:5535–5541.