Weijie Qin

Ph.D. and Postdoctoral Researcher from National University of Singapore. Research direction focuses on new proteomics technologies and their applications in disease biomarker and drug target screening. Has developed a series of distinctive low-abundance and modified proteome enrichment materials and chemical labeling enrichment methods, as well as single-cell processing platforms and mass spectrometry analysis strategies, significantly improving identification sensitivity and scale. Focusing on glycoproteins as important diagnostic biomarkers and drug targets, has established multiple efficient enrichment, mass spectrometry identification, and data analysis methods, providing systematic tools for glycoproteomics research. Has published over 80 papers in internationally renowned journals such as JACS, Angew, Molecular Cell, Nature Chemical Biology, Nature Communications, Nucleic Acids Research, Chemical Science, and Analytical Chemistry. Has successively led National Major Scientific Research Program projects, National Major Scientific Instrument and Equipment Development Special Projects, National Key R&D Program projects, and National Natural Science Foundation General Projects. Received the Second Prize of National Science and Technology Progress Award in 2017. Academic committee member of the Mass Spectrometry Branch of the Chinese Physical Society, committee member of the Mass Spectrometry Analysis Professional Committee of the Chinese Chemical Society, committee member of the Proteomics Professional Committee and Glycoconjugate Professional Committee of the Chinese Society for Biochemistry and Molecular Biology. Editorial board member of Chinese Chemical Letters.

1. Sun; H. F.; Fu, B.; Qian, X. H.; Xu, P. and Qin, W. J.*. Nuclear and cytoplasmic specific RNA binding proteome enrichment and its changes upon ferroptosis induction, Nat. Commun. 2024, 15, 852.
2. Kong, L. L.; Li, F. Z.; Fang, W.; Du, Z. K.; Wang, G. B.; Zhang, Y. J.; Ge, W. P.; Zhang, W. J. and Qin, W. J.*. Sensitive N-Glycopeptide Profiling of Single and Rare Cells Using an Isobaric Labeling Strategy without Enrichment, Anal. Chem. 2023, 95, 11326 (Cover Article).
3. Zhang, Z.#; Liu, T.#; Dong, H. Y.; Li, J.; Sun, H. F.; Qian, X. H. and Qin W. J.*, An RNA Tagging Approach for System-wide RNA-binding Proteome Profiling and Dynamics Investigation upon Transcription Inhibition, Nucleic Acids Res., 2021, 49, e65.