Yong Zhang

Dr. Zhang earned his Ph.D. in Medical Proteomics from the Academy of Military Sciences, PLA, from 2015 to 2018. He conducted postdoctoral research at West China Hospital of Sichuan University from 2018 to 2021, served as an Assistant Research Fellow at the same institution from 2021 to 2023, and has been an Associate Research Fellow there since 2023. Dr. Zhang currently serves as a Council Member of the Bioinformatics Society of Sichuan Province (BISSC) and Secretary-General of the Youth Committee of the Sichuan Association for the Promotion of Anti-Aging Scientific Research. Dr. Zhang’s primary research focus is clinical translational glycoproteomics, dedicated to the development of clinical glycoproteomic technologies and their translational applications. His work centers on establishing novel materials, technologies, methods, and algorithms for proteomics and post-translational modifications, conducting basic and applied research in major diseases to elucidate the molecular mechanisms of disease pathogenesis, identifying biomarkers or therapeutic targets with diagnostic, therapeutic, or prognostic value in clinical samples, and developing therapeutic agents or strategies for clinical translation. He has led or participated in more than 10 research projects, including the National Key Research and Development Program of China, the Major Research Plan of the National Natural Science Foundation of China (NSFC), General Programs, Young Scientists Fund, the China Postdoctoral Science Foundation, and projects funded by the Department of Science and Technology of Sichuan Province and the Health Commission of Sichuan Province. As first or corresponding author, he has published over 100 high-impact papers in journals including ACS Nano、Biomarker Research、MedComm、eLife、Aging & Disease、Molecular & Cellular Proteomics、Journal of Proteome Research. As first or major inventor, he has filed or been granted more than 10 Chinese invention patents. He has contributed as a co-author to the monograph Proteome Informatics and received one First-Class Provincial/Ministerial Prize for Scientific and Technological Progress.

Seleceted publications:
1. Yong Zhang(#), Hongyu Jing(#), Tao Wen, Yao Wang, Yang Zhao, Xiangke Wang*, Xiaohong Qian*, Wantao Ying*, Phenylboronic acid functionalized C3N4 facultative hydrophilic materials for enhanced enrichment of glycopeptides, Talanta, 191, 509-518, 2019-1-1, DOI:10.1016/j.talanta.2018.09.016
2. Yong Zhang(#)，Wanjun Zhao(#)，Yonghong Mao，Yaohui Chen，Shisheng Wang，Yi Zhong，Tao Su，Meng Gong，Dan Du，Xiaofeng Lu，Jingqiu Cheng*，Hao Yang*，Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins，Molecular & Cellular Proteomics，2021.02
3. Guizhen Yu(#), Yong Zhang(#), Bo Meng, Xinfang Xie, Zi Wang, Wantao Ying*, Jicheng Lv*, Hong Zhang, O-glycoforms of polymeric immunoglobulin A1 in the plasma of patients with IgA nephropathy are associated with pathological phenotypes, Nephrology Dialysis Transplantation, 2021-6-21
4. Honglei Zhang†*, Chao Liu†, Shuting Wang†, Qing Wang†, Xu Feng, Huawei Jiang, Yong Zhang*, Xiaosan Su*, Gaofeng Li*, Proteogenomic analysis of air-pollution-associated lung cancer reveals prevention and therapeutic opportunities. eLife, 2024.10，DOI: 10.7554/eLife.95453
5. Wenjuan Zeng#, Yong Zhang#, Xinyuan Wang#, Shisheng Wang, Tianhai Lin, Tao Su, Youmei Jin, YujiaYuan, Mengqi Luo, Yi Zhong, Dingkun Zhang, Meng Gong, Jingqiu Cheng, Jingping Liu, Shan Liu*, Weiya Wang*, Lu Yang*, Hao Yang*, Chemical Affinity Capture of Plasma Extracellular Vesicles Enables Rapid and Large-Scale Proteomic Identification of Novel Prostate Cancer Biomarkers，ACS Nano, 2025.04